Millipore Sigma Vibrant Logo

444251 MMP-2/MMP-9 Inhibitor III - Calbiochem

The MMP-2/MMP-9 Inhibitor III controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-2/MMP-9 Inhibitor III - Calbiochem: Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Primary Target: MMP-2, MMP-9
View Products on Sigmaaldrich.com
444251
Ver preços e disponibilidade

Panorama geral

Replacement Information

Tabela com principais espec.

Empirical Formula
C₅₂H₇₁N₁₃O₁₄S₂

Preço e Disponibilidade

Número de catálogo DisponibilidadeEmbalagem Qtde/Emb. Preço Quantidade
444251-1MG
Verificando a disponibilidade...
—
Disponibilidade limitada Disponibilidade limitada
Insira quantidade 
Descontinuado
Quantidades limitadas disponíveis
Disponibilidade a ser confirmada
    Restante: será informado
      Restante: será informado
      Vai informar
      Contatar o serviço de atendimento ao cliente
      Contact Customer Service

      		 Ampola plástica 1 mg
      Recuperando preço...
      O preço não pôde ser recuperado
      Quantidade mínima necessária para ser múltipla de
      Maximum Quantity is
      Após finalização do pedido Mais informações
      Você salvou ()
       
      —
      Solicitar preço
      		 —
      Description
      OverviewA hydrophobic cyclic peptide that acts as a potent inhibitor of MMP-2 and MMP-9 (IC50 = 10 µM). Inhibits the migration of human endothelial cells and tumor cells, and prevents tumor growth and invasion in animal models. Also, phage that display this peptide specifically targets angiogenic blood vessels in vivo.
      Catalogue Number444251
      Brand Family Calbiochem®
      References
      ReferencesMedina, O.P., et al. 2001. Cancer Res. 61, 3978.
      Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.
      Product Information
      ATP CompetitiveN
      DeclarationSold under license of U.S. Patent 6,624,144.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₅₂H₇₁N₁₃O₁₄S₂
      Chemical formulaC₅₂H₇₁N₁₃O₁₄S₂
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-2, MMP-9
      Primary Target IC<sub>50</sub>10 µM against MMP-2 and MMP-9
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Cys¹-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys¹⁰-OH (cyclic: 1→ 10)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      444251-1MG 04055977186512

      Documentation

      MMP-2/MMP-9 Inhibitor III - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      MMP-2/MMP-9 Inhibitor III - Calbiochem Certificados de análise

      TítuloNúmero do lote
      444251

      Referências

      Visão geral de referência
      Medina, O.P., et al. 2001. Cancer Res. 61, 3978.
      Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2008 RFH
      DescriptionA cyclic peptide that acts as a potent inhibitor of MMP-2 (gelatinase A; IC50 = 10 µM) and MMP-9 (gelatinase B; IC50 = 10 µM). Inhibits the migration of human endothelial cells and tumor cells, and prevents tumor growth and invasion in animal models.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₅₂H₇₁N₁₃O₁₄S₂
      Peptide SequenceH-Cys¹-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys¹⁰-OH (cyclic: 1→ 10)
      Purity≥97% by HPLC
      SolubilityH₂O (5 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Standard Handling
      ReferencesMedina, O.P., et al. 2001. Cancer Res. 61, 3978.
      Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.