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HNDG2MAG-36K MILLIPLEX MAP Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.

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Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Neuroscience Research Sub-Category: Alzheimer's Disease, Nervous System
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HNDG2MAG-36K
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Replacement Information

Tabela com principais espec.

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
α1-Antitrypsin Complement C4 CRP MIP-4 PEDF SAP HMplexLuminex xMAP
Description
Catalogue NumberHNDG2MAG-36K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay
Background InformationNeurodegenerative disease is a condition characterized by the deterioration of neurons or their myelin sheath over time in the brain and/or spinal cord. These neurons are responsible for such everyday activities as processing sensory information, making decisions, and controlling movement. Because these cells are not easily regenerated, excessive cumulative damage can lead to age-related diseases such as Alzheimer's and Parkinson's disease, as well as other conditions such as amyotrophic lateral sclerosis (ALS) and epilepsy. These disorders are devastating and expensive, both on a personal and global level, and as population demographics continue to change, a therapeutic solution is critical. Consequently, research is underway to identify biomarkers that will help scientists not only understand the pathogenesis of neurodegenerative disease, but also identify people with these disorders before the onset of symptoms and potentially provide new therapeutic tools.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay:<10
  • Inter-assay: <15
Panel TypeMAGNETIC Neuroscience
Quality LevelMQ200
Applications
ApplicationThe analytes available for this multiplex kit are: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.
Key Applications
  • Multiplexing
Application Notes• This is an overnight assay.
• This assay requires 25 μL of 1:2,000 diluted serum/plasma or 1:20 diluted CSF per well.
Biological Information
Species Reactivity
  • Human
Analytes Available
  • α1-Antitrypsin
  • Complement C4
  • CRP
  • MIP-4
  • PEDF
  • SAP
Assay PanelEverything you need in a single kit.
Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Accuracy
  • α-1-Antitrypsin 92%
  • Complement C4 88%
  • CRP 93%
  • MIP-4 95%
  • PEDF 92%
  • SAP 84%
Physicochemical Information
Sensitivity
  • See kit protocol for individual sensitvities
Standard Curve Range
  • α-1-Antitrypsin: 0.24-1,000 ng/mL
  • Complement C4: 0.24-1,000 ng/mL
  • CRP: 0.10-50 ng/mL
  • MIP-4: 4.88-20,000 ng/mL
  • PEDF: 0.05-200 ng/mL
  • SAP: 0.12-500 ng/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de catálogo GTIN
HNDG2MAG-36K 04053252987557

Documentation

MILLIPLEX MAP Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay MSDS

Título

Ficha de Segurança de Produtos (MSDS) 

Referências

Visão geral das referênciasPub Med ID
Plasma proteins predict conversion to dementia from prodromal disease.
Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, Zucht HD, Pepin D, Zheng W, Tunnicliffe A, Richardson J, Gauthier S, Soininen H, K³oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S.
Alzheimers Dement. 2014 Nov;10(6):799- 807.e2  2014

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Brochura

Título
The Power of Biomarker Analysis

Informações técnicas

Título
96 well Template 2 Up
96 well Template Single
HNDG2MAG-36K xPonent Protocol Template Version 3.1
Quality Control Range Sheet- HNDG2-111 and HNDG-211
Quality Control Ranges: Milliplex Human Neurodegenerative Magnetic Bead Panel 2 Kit Catalogue # HNDG2-36K

Pôster

Título
Inflammation in Neurodegenerative Diseases
Toxicology in drug discovery and development: Biomarkers and model organisms