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48-621MAG MILLIPLEX MAP DNA Damage/Genotoxicity Magnetic Bead Panel - Cell Signaling Multiplex Assay

Intracellular Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous relative quantitation of multiple phosphorylation and total pathway proteins in tissue and cell lysate samples. Compare Multiplexing results to those of Western blotting.

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Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Cell Signaling
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48-621MAG
96-well plate  
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      Replacement Information

      Tabela com principais espec.

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      ATR (Total) Chk1 (Ser345) Chk2 (Thr68) H2A.X (Ser139) MDM2 (total) p21 (Total) p53 (Ser15) H, M, RMplexLuminex xMAP
      Description
      Catalogue Number48-621MAG
      Trade Name
      • MILLIPLEX
      DescriptionMILLIPLEX MAP DNA Damage/Genotoxicity Magnetic Bead Panel - Cell Signaling Multiplex Assay
      OverviewThe MILLIPLEX® MAP 7-plex DNA Damage/Genotoxicity Magnetic Bead Kit (Cat. No. 48-621MAG) is a premixed kit to be used for the simultaneous quantification of the following 7 analytes in cell lysates:

      • ATR (total)
      • Chk1 (Ser345)
      • Chk2 (Thr68)
      • H2A.X (Ser139)
      • MDM2 (total)
      • p21 (total)
      • p53 (Ser15)
      References
      Product Information
      Detection methodLuminex xMAP
      HS Code3002 15 90
      ConfigurationPremixed
      Panel TypeCell Signaling
      Quality LevelMQ200
      Applications
      ApplicationIntracellular Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous relative quantitation of multiple phosphorylation and total pathway proteins in tissue and cell lysate samples. Compare Multiplexing results to those of Western blotting.
      Key Applications
      • Multiplexing
      Application Notes• An overnight (4°C) incubation is recommended for best results.
      • This assay requires 25 µL diluted cell lysate per well.
      • This kit must be run using Assay Buffer 1 (provided).
      • The suggested working range of protein concentration for the assay is 1 to 25 µg of total protein/well (25 μL/well at 40 to 1,000 µg/mL).
      Biological Information
      SpecificityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Analytes Available
      • ATR (Total)
      • Chk1 (Ser345)
      • Chk2 (Thr68)
      • H2A.X (Ser139)
      • MDM2 (total)
      • p21 (Total)
      • p53 (Ser15)
      Assay PanelEverything you need in a single kit.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommended storage for kit components is 2 - 8°C.
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      48-621MAG 04053252936067

      Documentation

      Protocols

      Title
      Protocol- 48-621MAG

      MILLIPLEX MAP DNA Damage/Genotoxicity Magnetic Bead Panel - Cell Signaling Multiplex Assay MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      Brochura

      Título
      The Power of Biomarker Analysis

      Informações técnicas

      Título
      96 well Template 2 Up
      96 well Template Single
      Exploring DNA Damage/Genotoxicity Using the MILLIPLEX®MAP 7-plex DNA Damage/Genotoxicity Kit

      Pôster

      Título
      Toxicology in drug discovery and development: Biomarkers and model organisms