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420321 KT5823 - CAS 126643-37-6 - Calbiochem

Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

KT5823 - CAS 126643-37-6 - Calbiochem: Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.

Sinônimos: PKG Inhibitor VII

Primary Target: PKG
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Replacement Information

Tabela com principais espec.

CAS #Empirical Formula
126643-37-6C₂₉H₂₅N₃O₅

Preço e Disponibilidade

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420321-100UG
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      Description
      OverviewHighly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
      Catalogue Number420321
      Brand Family Calbiochem®
      SynonymsPKG Inhibitor VII
      References
      ReferencesGrider, J.R. 1993. Am. J. Physiol. 264, G334.
      Product Information
      CAS number126643-37-6
      ATP CompetitiveY
      FormWhite solid
      Hill FormulaC₂₉H₂₅N₃O₅
      Chemical formulaC₂₉H₂₅N₃O₅
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKG
      Primary Target K<sub>i</sub>234 nM against protein kinase G
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      420321-100UG 04055977211047

      Documentation

      KT5823 - CAS 126643-37-6 - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      KT5823 - CAS 126643-37-6 - Calbiochem Certificados de análise

      TítuloNúmero do lote
      420321

      Referências

      Visão geral de referência
      Grider, J.R. 1993. Am. J. Physiol. 264, G334.

      Citações

      Título
    • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
    • Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology 289, L196-L206.
      		•
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-July-2008 RFH
      SynonymsPKG Inhibitor VII
      DescriptionHighly specific cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). Inhibits protein kinase C (Ki = 4.0 µM) and protein kinase A (Ki > 10.0 µM) at higher concentrations.
      FormWhite solid
      CAS number126643-37-6
      Chemical formulaC₂₉H₂₅N₃O₅
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMF or DMSO (1 mg/ml). Further dilute with aqueous buffers just prior to use.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesGrider, J.R. 1993. Am. J. Physiol. 264, G334.
      Citation
    • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
    • Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology 289, L196-L206.
      		•