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420355 Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem

Phenethylamine derivative.

Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Primary Target: β-adrenergic agonist
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420355
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Tabela com principais espec.

CAS #Empirical Formula
51-30-9C₁₁H₁₇NO₃ · HCl

Preço e Disponibilidade

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420355-100MG
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      Description
      OverviewPhenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.
      Catalogue Number420355
      Brand Family Calbiochem®
      References
      ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.
      Product Information
      CAS number51-30-9
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₁₁H₁₇NO₃ · HCl
      Chemical formulaC₁₁H₁₇NO₃ · HCl
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetβ-adrenergic agonist
      Purity≥99% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSDO1925000
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      420355-100MG 04055977187533

      Documentation

      Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem Certificados de análise

      TítuloNúmero do lote
      420355

      Referências

      Visão geral de referência
      Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.

      Brochura

      Título
      Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2008 RFH
      DescriptionPhenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
      FormWhite to off-white solid
      CAS number51-30-9
      RTECSDO1925000
      Chemical formulaC₁₁H₁₇NO₃ · HCl
      Structure formulaStructure formula
      Purity≥99% by TLC
      SolubilityEthanol or H₂O
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Irritant
      Merck USA index14, 5217
      ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
      Carmena, M.J., et al. 1997. Prostate 33, 46.
      Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
      Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
      Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
      Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
      Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
      von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
      Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.