189826 Sigma-AldrichInSolution™ 5-Aza-2ʹ-Deoxycytidine - CAS 2353-33-5 - Calbiochem
A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines.
More>> A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Less<<Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Sinônimos: Decitabine
Produtos recomendados
Panorama geral
| Replacement Information |
|---|
Tabela com principais espec.
| CAS # | Empirical Formula |
|---|---|
| 2353-33-5 | C₈H₁₂N₄O₄ |
Preço e Disponibilidade
| Número de catálogo | Disponibilidade | Embalagem | Qtde/Emb. | Preço | Quantidade | |
|---|---|---|---|---|---|---|
| 189826-10MG |
|
Frasco de vidro | 10 mg |
|
— |
| Description | |
|---|---|
| Overview | A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. The solid form of this compound (Cat. No. 189825) is also available. |
| Catalogue Number | 189826 |
| Brand Family | Calbiochem® |
| Synonyms | Decitabine |
| Product Information | |
|---|---|
| CAS number | 2353-33-5 |
| Form | Liquid |
| Formulation | A 100 mM (10 mg/438 µl) solution of 5-Aza-2ʹ-Deoxycytidine (Cat. No. 189825) in DMSO. |
| Hill Formula | C₈H₁₂N₄O₄ |
| Chemical formula | C₈H₁₂N₄O₄ |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥ 98% by HPLC |
| Physicochemical Information |
|---|
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Número de catálogo | GTIN |
| 189826-10MG | 04055977222050 |
Documentation
InSolution™ 5-Aza-2ʹ-Deoxycytidine - CAS 2353-33-5 - Calbiochem MSDS
| Título |
|---|
InSolution™ 5-Aza-2ʹ-Deoxycytidine - CAS 2353-33-5 - Calbiochem Certificados de análise
| Título | Número do lote |
|---|---|
| 189826 |
Referências
| Visão geral de referência |
|---|
| Eggert, A., et al. 2001. Cancer Res. 61, 1314. Takebayashi, S., et al. 2001. Biochem. Biophys. Res. Commun. 288, 921. Zhu, W.G., et al. 2001. Cancer Res. 61, 1327. Hopkins-Donaldson, S., et al. 2000. Cancer Res. 60, 4315. Haaf, T. 1995. Pharmacol. Ther. 65, 19. Jones, P.A., and Taylor, S.M. 1980. Cell 20, 85. |
Informações técnicas
| Título |
|---|
| White Paper - The Message in the Marks: Deciphering Cancer Epigenetics |
| Ficha de dados | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|