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116801 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem

A key regulator of many cellular reactions.

Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.

Sinônimos: A-3:5-MP, cAMP, Na

Primary Target: Protein kinase A
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116801
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CAS #Empirical Formula
37839-81-9C₁₀H₁₁N₅O₆P · Na

Preço e Disponibilidade

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116801-100MG
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      Description
      OverviewA key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.
      Catalogue Number116801
      Brand Family Calbiochem®
      SynonymsA-3:5-MP, cAMP, Na
      References
      ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
      de Rooij, J., et al. 1998. Nature 396, 474.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.
      Product Information
      CAS number37839-81-9
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₀H₁₁N₅O₆P · Na
      Chemical formulaC₁₀H₁₁N₅O₆P · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetProtein kinase A
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSAU7357900
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      116801-100MG 04055977208191

      Documentation

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem Certificados de análise

      TítuloNúmero do lote
      116801

      Referências

      Visão geral de referência
      Kawasaki, H., et al. 1998. Science 282, 2275.
      de Rooij, J., et al. 1998. Nature 396, 474.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-April-2008 RFH
      SynonymsA-3:5-MP, cAMP, Na
      DescriptionA key regulator of many cellular reactions. Second messenger molecule released in response to hormonal stimulation. An activator of protein kinase A. Induces the guanine-nucleotide-exchange factor activity of GEFI, also known as Epac (exchange protein directly activated by cAMP), and GEFII towards Rap1 both in vitro and in vivo. Promotes apoptosis in resting human B lymphocytes.
      FormWhite solid
      CAS number37839-81-9
      RTECSAU7357900
      Chemical formulaC₁₀H₁₁N₅O₆P · Na
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 2708
      ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
      de Rooij, J., et al. 1998. Nature 396, 474.
      Lomo, J., et al. 1995. J. Immunol. 154, 1634.