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Chromolith® Prep


Comparison of Flow Rates

Chromolith® Prep columns for preparative chromatography can be operated with a flow rate of up to 400 mL/min, and pressures of up to 100 bar. This presents a tenfold increase in flow rate compared to particulate packed columns of an equivalent size.

Separation at different flow rates: 40 and 390 mL/min

Chromolith® Prep Si 100-25 mm at 40 mL/min
Column Chromolith® Prep Si 100-25 mm
Solvent n-Heptane/Dioxane (80/20 v/v) q
Flow rate 40 mL/min
Sample 1. Toluene
2. Dimethylphthalate
3. Dibutylphthalate
Chromolith® Prep Si 100-25 mm at 40 mL/min
Chromolith® Prep Si 100-25 mm at 390 mL/min
Column Chromolith® Prep Si 100-25 mm
Solvent n-Heptane/Dioxane (80/20 v/v)
Flow rate 390 mL/min
Sample 1. Toluene
2. Dimethylphthalate
3. Dibutylphthalate
 Chromolith® Prep Si 100-25 mm at 390 mL/min
Separation of diastereomers with a productivity of 861 g/d

Column Chromolith® Prep Si 100-25 mm
Solvent n-Heptane / Dioxane (80/20 v/v)
Flow rate 140 mL/min
Injection 249 mg
Cycle Time 25 sec
Sample Fluoro-dihydro-oxyranyl-benzopyran
Chromolith® Prep Si 100-25 mm

Chromolith® Prep Product Range

The ready-to-use columns are cladded with a polymeric material (PEEK), and can be connected directly to any HPLC system.

  • Chromolith® Prep Si: Learn More
  • Chromolith® Prep RP-18-e: Learn More
  • Chromolith® Prep Guard Cartridge Si: Learn More
  • Chromolith® Prep Guard Cartridge RP-18e: Learn More
  • Chromolith® Prep Sealing Set (2 O-rings): Learn more
  • Chromolith® Prep Tool Set(1 mounting tool filter, 1 mounting tool, 1 hook wrench): Learn More
  • Chromolith® Prep Endcap Set(1 inlet cap complete, 1 outlet cap): Learn More
  • Chromolith® Prep Frit Set(10 frits): Learn More
  • Chromolith® Prep 25 mm Column Coupler: Learn More
 
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HPLC Application Collections

Application Notes and Methods

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