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567860 Sigma-AldrichSRT1720 - CAS 925434-55-5 - Calbiochem
SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56 µM; Km = 2.44 µM), but NAD+-uncompetitive (Ki = 0.34 µM; Km = 280 µM).
345887 Sigma-AldrichGinkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem
Ginkgolic Acid (15:1), CAS 22910-60-7, is a cell-permeable analog of anacardic acid that inhibits protein SUMOylation (IC50 = 3.0 µM using RanGAP1-C2 as substrate) in an ATP-dependent manner.
239802 Sigma-AldrichCurcumin, Curcuma longa L. - CAS 458-37-7 - Calbiochem
A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM).
373260 Sigma-AldrichHeat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem
Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner.
