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108386 Tris(hydroxymethyl)aminomethane

(Trometamol) EMPROVE® EXPERT Ph Eur,BP,ChP,JPC,USP

Tris(hydroxymethyl)aminomethane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 77-86-1 EC Number: 201-064-4 Molar Mass: 121.14 g/mol Chemical Formula: H₂NC(CH₂OH)₃ Hill Formula: C₄H₁₁NO₃ Grade: Ph Eur,BP,ChP,JPC,USP
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108386
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

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1083861000
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      1083865000
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          1083869013
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              1083869025
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                  Description
                  Catalogue Number108386
                  SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                  DescriptionTris(hydroxymethyl)aminomethane
                  References
                  Product Information
                  CAS number77-86-1
                  EC number201-064-4
                  GradePh Eur,BP,ChP,JPC,USP
                  Hill FormulaC₄H₁₁NO₃
                  Chemical formulaH₂NC(CH₂OH)₃
                  Molar Mass121.14 g/mol
                  HS Code2922 19 99
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Boiling point219 - 220 °C (13.3 hPa)
                  Density1.32 g/cm3 (20 °C)
                  Melting Point169 °C
                  pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
                  Vapor pressure<0.1 hPa (20 °C)
                  Bulk density840 kg/m3
                  Solubility678 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat > 5000 mg/kg
                  LD 50 dermalLD50 Rat > 5000 mg/kg
                  Safety Information according to GHS
                  RTECSTY2900000
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageNoTempLimit
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications
                  Global Trade Item Number
                  Catalogue Number GTIN
                  1083861000 04022536103846
                  1083865000 04022536775487
                  1083869013 04027269174378
                  1083869025 04022536103853

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  6.0

                  Quality Management Dossier (Open Access)

                  Title

                  Operational Excellence Dossier

                  Title

                  Tris(hydroxymethyl)aminomethane SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Tris(hydroxymethyl)aminomethane Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1083861000 Plastic bottlePDF Specification Document
                  1083865000 Plastic bottlePDF Specification Document
                  1083869013 Bucket, plasticPDF Specification Document
                  1083869025 PDF Specification Document

                  Certificates

                  Title

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                  Categories

                  Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
                  Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
                  Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
                  Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers