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100894 Sucralose powder

Overview

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
56038-13-2259-952-2C₁₂H₁₉Cl₃O₈397.63 g/molPh Eur,ChP,NF,JPE

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1008940010
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      Glass bottle 10 g
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      1008941000
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          Fibre carton 1 kg
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          1008949010
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              Fibre carton 10 kg
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              Description
              Catalogue Number100894
              Product Information
              CAS number56038-13-2
              EC number259-952-2
              GradePh Eur,ChP,NF,JPE
              Hill FormulaC₁₂H₁₉Cl₃O₈
              Molar Mass397.63 g/mol
              HS Code2932 14 00
              Structure formula ImageStructure formula Image
              Quality LevelMQ500
              Physicochemical Information
              Density1.62 g/cm3 (20 °C) Not applicable
              Melting Point114.5 °C (decomposition)
              pH value6 - 8 (100 g/l, H₂O, 20 °C)
              Solubility300 g/l
              Toxicological Information
              LD 50 oralLD50 Rat > 10000 mg/kg
              Safety Information according to GHS
              RTECSLW5440140
              Storage class10 - 13 Other liquids and solids
              WGKWGK 2 obviously hazardous to water
              Disposal3
              Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
              Storage and Shipping Information
              StorageStore at +15°C to +25°C.
              Transport Information
              Declaration (railroad and road) ADR, RIDKein Gefahrgut
              Declaration (transport by air) IATA-DGRUN 1845 , 9,
              Declaration (transport by sea) IMDG-CodeUN 1845 , 9,
              Specifications
              Assay (HPLC, calc. on anhydrous substance)98.0 - 102.0 %
              Assay (HPLC, calc. on anhydrous substance) (ChP)98.0 - 102.0 %
              Assay (calc. on anhydrous substance) (JPE)98.0 - 102.0 %
              Appearance of substance (description)balled powder
              Appearance of substance (color)almost white
              Identity (HPLC)conforms
              Identity (TLC)conforms
              Identity (IR)conforms
              Identity (Spec. rotation (Ph Eur))conforms
              Spec. Rotation [α²0/D (calc. on anhydrous substance) (Ph Eur/JPE)+84.0 - +87.5 °
              Spec. Rotation [α²0/D (calc. on anhydrous substance) (NF/ChP)+84.0 - +87.5 °
              Appearance of solution (10 %, water)conforms
              pH-TestDecrease of 1 pH unit max.
              Heavy metals (as Pb)≤ 0.0010 %
              Methanol≤ 0.1 %
              Methanol (ChP)≤ 0.1 %
              Cyclohexane≤ 3880 ppm
              N,N-Dimethylformamide≤ 880 ppm
              Acetic acid≤ 5000 ppm
              Ethyl acetate≤ 5000 ppm
              Other residual solvents (ICH Q3C)excluded by production process
              Hydrolysis products≤ 0.1 %
              Impurities H and I≤ 0.1 %
              Monosaccharide-Chloride (as Fructose)≤ 0.16 %
              Related substances (Ph Eur/ChP)≤ 0.5 %
              Related substances (NF)≤ 0.5 %
              Other Disaccharide-Chlorides≤ 0.5 %
              Triphenylphosphine oxide≤ 150 ppm
              Residue on ignition≤ 0.7 %
              Water (according to Karl Fischer)≤ 2.0 %
              Particle Size (d90)≤ 12 µm
              Microbiological purity (Total aerobic microbial count (TAMC))≤ 1E+03 CFU/g
              Microbiological purity (Total yeast and mould count (TYMC))≤ 1E+02 CFU/g
              Bile tolerant Gram negative Bacteria (absent in 1 g)conforms
              Escherichia coli (absent in 1 g)conforms
              Pseudomonas aeruginosa (absent in 1 g)conforms
              Staphylococcus aureus (absent in 1 g)conforms
              Candida albicans (absent in 1 g)conforms
              Salmonella ssp (absent in 10 g)conforms
              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
              Corresponds to Ph Eur, ChP, NF, JPE
              Global Trade Item Number
              Catalogue Number GTIN
              1008940010 04027269161323
              1008941000 04027269161347
              1008949010 04027269161361