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181198 Arachidonic Acid - CAS 506-32-1 - Calbiochem

Precursor for prostaglandins, prostacyclin, and thromboxane.

Arachidonic Acid - CAS 506-32-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4

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181198
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
506-32-1C₂₀H₃₂O₂

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181198-100MG
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      		 Glass bottle 100 mg
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      Description
      OverviewPrecursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway.
      Catalogue Number181198
      Brand Family Calbiochem®
      Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
      References
      ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
      Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
      Han, J.-W., et al. 1991. Science 252, 576.
      Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
      Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.
      Product Information
      CAS number506-32-1
      ATP CompetitiveN
      FormColorless oil
      Hill FormulaC₂₀H₃₂O₂
      Chemical formulaC₂₀H₃₂O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetRas-GAP
      Purity≥99% by TLC and GC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSCE6675000
      Safety Information
      R PhraseR: 20/21/22-36/37/38

      Harmful by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 36-26

      Wear suitable protective clothing.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Harmful
      Storage ≤ -70°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      181198-100MG 04055977205008

      Documentation

      Arachidonic Acid - CAS 506-32-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Arachidonic Acid - CAS 506-32-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      181198

      References

      Reference overview
      Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
      Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
      Han, J.-W., et al. 1991. Science 252, 576.
      Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
      Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-April-2008 RFH
      Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
      DescriptionA cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets.
      FormColorless oil
      Intert gas (Yes/No) Packaged under inert gas
      CAS number506-32-1
      RTECSCE6675000
      Chemical formulaC₂₀H₃₂O₂
      Structure formulaStructure formula
      Purity≥99% by TLC and GC
      SolubilityEthanol (5 mg/ml)
      Storage Protect from light
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful
      Merck USA index14, 765
      ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
      Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
      Han, J.-W., et al. 1991. Science 252, 576.
      Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
      Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.