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14-478M Yes Protein, active, 250 µg

Active, recombinant full-length human Yes, containing additional N-terminal His6 tag, for use in Kinase Assays.

Yes Protein, active, 250 µg : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
14-478M
250 µg  Also available in 10 μg size (cat#14-478) and in bulk (cat# 14-478-K).
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue Number14-478M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionYes Protein, active, 250 µg
OverviewRecombinant full-length human Yes, containing additional N-terminal His6 tag
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, recombinant full-length human Yes, containing additional N-terminal His6 tag, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThis gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Gene Symbol
  • YES1
  • P61-YES
  • HsT441
  • Yes
  • c-yes
  • YES
  • p61-Yes
Protein TargetYes
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P07947 # Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
SIZE: 543 amino acids; 60801 Da
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Note=In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
PTM: Autophosphorylated.
SIMILARITY: SwissProt: P07947 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight63kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of Poly (Glu4-Tyr) substrate
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-478) and in bulk (cat# 14-478-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-478M 04053252740268

Produits & Applications associés

Alternative Packsize

Référence Description
14-478 Yes Protein, active, 10 µg

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Catégories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases