676496 Sigma-AldrichVEGF Inhibitor, CBO-P11 - Calbiochem
VEGF Inhibitor, CBO-P11, is a macrocyclic peptide derived from residues 79-93 of VEGF. Mediates VEGF binding to VEGFR-2. Blocks VEGF165 binding to VEGFR1 and 2 (IC50 = 700 nM & 1.3 µM, respectivel
More>> VEGF Inhibitor, CBO-P11, is a macrocyclic peptide derived from residues 79-93 of VEGF. Mediates VEGF binding to VEGFR-2. Blocks VEGF165 binding to VEGFR1 and 2 (IC50 = 700 nM & 1.3 µM, respectively). Less<<Synonymes: Cyclo-VEGI, cyclic(D-F-PQIMRIKPHQGQHIGE), D-Phe-Pro(79-93), VEGFR Tyrosine Kinase Inhibitor XX, VEGFR2 Kinase Inhibitor XVI
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Aperçu
Tableau de caractéristiques principal
Empirical Formula |
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C₉₀H₁₄₀N₂₈O₂₂S |
Products
Référence | Conditionnement | Qté | |
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676496-1MG | Ampoule plast. | 1 mg |
References | |
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References | Zilberberg, L., et al. 2003. J. Biol. Chem. 278, 35564. |
Product Information | |
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ATP Competitive | N |
Form | White lyophilized solid |
Formulation | Supplied as a trifluoroacetate salt. |
Hill Formula | C₉₀H₁₄₀N₂₈O₂₂S |
Chemical formula | C₉₀H₁₄₀N₂₈O₂₂S |
Hygroscopic | Hygroscopic |
Reversible | N |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | Blocks the binding of VEGF165 to its receptors |
Primary Target IC<sub>50</sub> | 700 nM for VEGFR1, 1.3 µM for VEGFR2 |
Purity | ≥97% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Peptide Sequence | cyclic(D-Phe-Pro-Gln-Ile-Met-Arg-Ile-Lys-Pro-His-Gln-Gly-Gln-His-Ile-Gly-Glu) |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Référence | GTIN |
676496-1MG | 04055977260489 |