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AG382 Uncoupling Protein 1, control peptide for AB3038

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Gene Symbol: UCP1, Thermogenin, UCP, SLC25A7 UniProt Number: P25874
AG382
100 µg  
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Replacement Information
Description
Catalogue NumberAG382
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionUncoupling Protein 1, control peptide for AB3038
OverviewUncoupling Protein 1 (UCP1) control peptide.
Alternate Names
  • UCP1
References
Product Information
PresentationLiquid in PBS, pH 7.5 without a preservative
Quality LevelMQ300
Applications
Key Applications
  • Peptide Inhibition Assay
Application NotesAntibody blocking (AB3038)

Optimal working concentration must be determined by the end user.
Biological Information
Concentration1 mg/mL
Entrez Gene Number
Entrez Gene SummaryMitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
Gene Symbol
  • UCP1
  • Thermogenin
  • UCP
  • SLC25A7
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P25874 # UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
SIZE: 307 amino acids; 33005 Da
SUBUNIT: Acts as a dimer forming a proton channel.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Brown adipose tissue.
SIMILARITY: SwissProt: P25874 ## Belongs to the mitochondrial carrier family. & Contains 3 Solcar repeats.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
AG382 04053252678899