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662015 U18666A - CAS 3039-71-2 - Calbiochem

A cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol.

U18666A - CAS 3039-71-2 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl

Primary Target: Activity of δ8-sterol isomerase
662015
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
3039-71-2C₂₅H₄₁NO₂ • HCl

Products

RéférenceConditionnement Qté
662015-10MG Ampoule plast. 10 mg
Description
OverviewA cell-permeable, amphiphilic amino-steroid that alters intracellular membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol, presumably via its inhibitory effect on 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ8-sterol isomerase.
Catalogue Number662015
Brand Family Calbiochem®
Synonyms3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl
References
ReferencesHall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
Kobayashi, T., et al. 1998. Nature 392, 193.
Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.
Product Information
CAS number3039-71-2
ATP CompetitiveN
FormLyophilized white solid
Hill FormulaC₂₅H₄₁NO₂ • HCl
Chemical formulaC₂₅H₄₁NO₂ • HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetActivity of δ8-sterol isomerase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
662015-10MG 04055977261042

Documentation

U18666A - CAS 3039-71-2 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

U18666A - CAS 3039-71-2 - Calbiochem Certificats d'analyse

TitreNuméro de lot
662015

Références bibliographiques

Aperçu de la référence bibliographique
Hall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
Kobayashi, T., et al. 1998. Nature 392, 193.
Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-June-2017 JSW
Synonyms3β-(2-Diethylaminoethoxy)androst-5-en-17-one, HCl
DescriptionA cell-permeable, amphiphilic amino-steroid that alters intracelluar membrane protein trafficking by impairing intracellular biosynthesis and transport of LDL-derived cholesterol. Reported to exert its effects via the inhibition of 2,3-oxidosqualene-lanosterol cyclase activity. Also reported to inhibit the activity of Δ8-sterol isomerase.
FormLyophilized white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number3039-71-2
Chemical formulaC₂₅H₄₁NO₂ • HCl
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (10 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHall, A.M., et al. 2003. Pigment Cell Res. 16, 149.
Kobayashi, T., et al. 1998. Nature 392, 193.
Liscum, L. and Faust, J.R., 1989. J. Biol. Chem. 264, 11796.
Sexton, R.C., et al. 1983. Biochemistry 22, 5687.
Bierkamper, G.G. and Cenedella, R.J., 1978. Brain Res. 150, 343.