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616374 TRAIL, Human, Recombinant, E. coli

TRAIL, Human, Recombinant, E. coli : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Apo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli

616374
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Products

RéférenceConditionnement Qté
616374-100UG Ampoule plast. 100 μg
Description
OverviewRecombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.
Catalogue Number616374
Brand Family Calbiochem®
SynonymsApo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli
References
ReferencesLin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.
Product Information
FormLiquid
FormulationIn 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.
Quality LevelMQ100
Applications
Biological Information
Biological activityInduces apoptosis in U937 cells at 1 μg/ml within 5 h.
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Contaminantsendotoxin <0.1 EU/µg TRAIL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze
(-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
616374-100UG 04055977186246

Documentation

TRAIL, Human, Recombinant, E. coli FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

TRAIL, Human, Recombinant, E. coli Certificats d'analyse

TitreNuméro de lot
616374

Références bibliographiques

Aperçu de la référence bibliographique
Lin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
SynonymsApo2L, Human, Recombinant, E. coli, TNF-Related Apoptosis-Inducing Ligand, Human, Recombinant, E. coli
DescriptionRecombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.
FormLiquid
FormulationIn 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Contaminantsendotoxin <0.1 EU/µg TRAIL
Biological activityInduces apoptosis in U937 cells at 1 μg/ml within 5 h.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze
(-70°C).
Toxicity Standard Handling
ReferencesLin, Y., et al. 2000. Mol. Cell. Biol. 20, 6638.
Mitsaides, N., et al. 2000. Cancer Res. 60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med. 189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol. 137, 221.
Pan, G., et al. 1997. Science 276, 111.
Pan, G., et al. 1997. Science 277, 815.
Sheridan, J.P., et al. 1997. Science 277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem. 271, 12687.
Wiley, S.R., et al. 1995. Immunity 3, 673.