573102 Sigma-AldrichSTAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
More>> STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription. Less<<FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Synonymes: 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
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Aperçu
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Tableau de caractéristiques principal
| CAS # | Empirical Formula |
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| 501919-59-1 | C₁₆H₁₅NO₇S |
Products
| Référence | Conditionnement | Qté | |
|---|---|---|---|
| 573102-10MG | Ampoule plast. | 10 mg | |
| 573102-25MG | Ampoule plast. | 25 mg |
| Description | |
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| Overview | A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130). |
| Catalogue Number | 573102 |
| Brand Family | Calbiochem® |
| Synonyms | 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859 |
| References | |
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| References | Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
| Product Information | |
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| CAS number | 501919-59-1 |
| Form | Light beige solid |
| Hill Formula | C₁₆H₁₅NO₇S |
| Chemical formula | C₁₆H₁₅NO₇S |
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| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Référence | GTIN |
| 573102-10MG | 04055977266429 |
| 573102-25MG | 04055977266436 |
Documentation
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem FDS
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STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem Certificats d'analyse
| Titre | Numéro de lot |
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| 573102 |
Références bibliographiques
| Aperçu de la référence bibliographique |
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| Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Informations techniques
| Titre |
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| JAK/STAT Signaling Research Focus |