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14-666M SRPK2 Protein, active, 250 µg

Active, N-terminal GST-tagged, recombinant, human SRPK2, amino acids 46-end, for use in Kinase Assays.

14-666M
250 µg  Also available in 10 μg size (cat#14-666) and in bulk (cat#14-666-K).
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue Number14-666M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionSRPK2 Protein, active, 250 µg
OverviewN-terminal GST-tagged, recombinant, human SRPK2, amino acids 46-end
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal GST-tagged, recombinant, human SRPK2, amino acids 46-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed in E. coli
Entrez Gene Number
Gene Symbol
  • SRPK2
  • FLJ36101
  • WUGSC:H_RG152G17.1a
  • SFRSK2
  • H_RG152G17.1b
  • H_RG152G17.1a
Protein TargetSRPK2
Purification MethodGlutathione-agarose
Target Sub-FamilyCMGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P78362 # Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
COFACTOR: Magnesium.
SIZE: 688 amino acids; 77543 Da
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
TISSUE SPECIFICITY: Highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.
SIMILARITY: SwissProt: P78362 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Molecular Weight100kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of SRPKtide (Catalog # 12-532)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-666) and in bulk (cat#14-666-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-666M 04053252924651

Documentation

Produits & Applications associés

Alternative Packsize

Référence Description
14-666 SRPK2 Protein, active, 10 µg

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Catégories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases