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506272 SB 206553 Hydrochloride - CAS 158942-04-2 - Calbiochem

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553

Primary Target: 5-HT2C
506272
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
158942-04-2C₁₇H₁₆N₄O·HCl

Products

RéférenceConditionnement Qté
5062720001 Flacon en verre 10 mg
Description
OverviewA selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5 nM) and 5-HT2AR (Ki = 2,300 nM).
Catalogue Number506272
Brand Family Calbiochem®
Synonyms5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553
References
ReferencesRos, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.
Product Information
CAS number158942-04-2
FormYellow solid
Hill FormulaC₁₇H₁₆N₄O·HCl
Chemical formulaC₁₇H₁₆N₄O·HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-HT2C
Primary Target K<sub>i</sub>3.2 nM
Secondary target5-HT2B
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
5062720001 04055977243208

Documentation

SB 206553 Hydrochloride - CAS 158942-04-2 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Références bibliographiques

Aperçu de la référence bibliographique
Ros, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-September-2013 JSW
Synonyms5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553
DescriptionA selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5 nM) and 5-HT2AR (Ki = 2,300 nM).
FormYellow solid
CAS number158942-04-2
Chemical formulaC₁₇H₁₆N₄O·HCl
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesRos, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.