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559276 Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem

Ryanodine, High Purity - CAS 15662-33-6, is a naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum (IC50 = 10 nM for skeletal muscle).

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Primary Target: Ca2+ transport and action in muscle
559276
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
15662-33-6C₂₅H₃₅NO₉

Products

RéférenceConditionnement Qté
559276-500UG Ampoule plast. 500 μg
Description
OverviewNaturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. Has many complex effects on Ca2+ transport and action in muscle.
Catalogue Number559276
Brand Family Calbiochem®
References
ReferencesSorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133.
Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.
Product Information
CAS number15662-33-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₅H₃₅NO₉
Chemical formulaC₂₅H₃₅NO₉
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationRyanodine, High Purity - CAS 15662-33-6, is a naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum (IC50 = 10 nM for skeletal muscle).
Biological Information
Primary TargetCa2+ transport and action in muscle
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSVM4025000
Safety Information
R PhraseR: 21/22-50/53

Harmful in contact with skin and if swallowed.
Very toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
S PhraseS: 36/37-60-61

Wear suitable protective clothing and gloves.
This material and its container must be disposed of as hazardous waste.
Avoid release to the environment. Refer to special instructions/safety data sheet.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
559276-500UG 04055977192353

Documentation

Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem Certificats d'analyse

TitreNuméro de lot
559276

Références bibliographiques

Aperçu de la référence bibliographique
Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133.
Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-December-2007 JSW
DescriptionNaturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. Has many complex effects on Ca2+ transport and action in muscle. Purified from Ryanodine Mixture.
FormWhite solid
CAS number15662-33-6
RTECSVM4025000
Chemical formulaC₂₅H₃₅NO₉
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityMethanol (20 mg/ml) or H₂O (1 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
Toxicity Harmful
Merck USA index14, 8307
ReferencesSorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133.
Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.