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557450 Ruthenium Red - CAS 11103-72-3 - Calbiochem

A blocker of transmembrane Ca2+ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

Ruthenium Red - CAS 11103-72-3 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Ammoniated Ruthenium Oxychloride, RR

Primary Target: Blocker of transmembrane Ca2+ fluxes
557450
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
12790-48-6[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆

Products

RéférenceConditionnement Qté
557450-250MG Flacon en verre 250 mg
Description
OverviewA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
Catalogue Number557450
Brand Family Calbiochem®
SynonymsAmmoniated Ruthenium Oxychloride, RR
References
ReferencesMerck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.
Product Information
CAS number12790-48-6
ATP CompetitiveN
FormRed-black solid
Hill Formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetBlocker of transmembrane Ca2+ fluxes
Primary Target IC<sub>50</sub>7 µM in blocking transmembrane Ca2+ fluxes; 6 µM inhibiting K+-stimulated catecholamine secretion
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 22

Do not breathe dust.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
557450-250MG 04055977268096

Documentation

Ruthenium Red - CAS 11103-72-3 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Ruthenium Red - CAS 11103-72-3 - Calbiochem Certificats d'analyse

TitreNuméro de lot
557450

Références bibliographiques

Aperçu de la référence bibliographique
Merck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-May-2024 JSW
SynonymsAmmoniated Ruthenium Oxychloride, RR
DescriptionA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
FormRed-black solid
CAS number12790-48-6
Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
SolubilityH₂O or ammonia
Storage Protect from moisture
+15°C to +30°C
Do Not Freeze Ok to freeze
Toxicity Harmful
Merck USA index14, 8300
ReferencesMerck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.