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528240 Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: GPIIbIIIa, Fibrinogen Receptor, CD41/CD61

528240
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Aperçu

Replacement Information

Products

RéférenceConditionnement Qté
528240-1MG Ampoule plast. 1 mg
Description
OverviewNative, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
Catalogue Number528240
Brand Family Calbiochem®
SynonymsGPIIbIIIa, Fibrinogen Receptor, CD41/CD61
References
ReferencesSchwarz M., et al. 2004. J. Pharmacol. Exp. Therap. 308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl₂, 50% glycerol, ≤0.1% sodium azide, pH 7.4.
Quality LevelMQ100
Applications
Biological Information
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
528240-1MG 04055977196535

Documentation

Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets Certificats d'analyse

TitreNuméro de lot
528240

Références bibliographiques

Aperçu de la référence bibliographique
Schwarz M., et al. 2004. J. Pharmacol. Exp. Therap. 308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-January-2021 JSW
SynonymsGPIIbIIIa, Fibrinogen Receptor, CD41/CD61
DescriptionNative, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
FormLiquid
FormulationIn 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl₂, 50% glycerol, ≤0.1% sodium azide, pH 7.4.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.
Toxicity Standard Handling
ReferencesSchwarz M., et al. 2004. J. Pharmacol. Exp. Therap. 308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.