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14-650M PKG1β Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, full length PKG1β, for use in Kinase Assays.

14-650M
250 µg  Also available in 10 μg size (cat#14-650) and in bulk (cat#14-650-K).
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue Number14-650M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPKG1β Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, full length PKG1β
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, full length PKG1β, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Entrez Gene Number
Gene Symbol
  • PRKG1
  • cGKI-beta
  • FLJ36117
  • PGK
  • PRKGR1A
  • cGKI-alpha
  • cGKI
  • MGC71944
  • OTTHUMP00000061216
  • CGKI
  • PRKG1B
  • cGKI-BETA
  • PRKGR1B
  • DKFZp686K042
Protein TargetPKG1β
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummarySIZE: 686 amino acids; 77804 Da
SUBUNIT: Antiparallel homodimer. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1 (By similarity). Interacts with MRVI1.
DOMAIN: SwissProt: P14619
SIMILARITY: SwissProt: P14619 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. | Q13976 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain.
MISCELLANEOUS: Exhibit a substrate specificity similar but not identical to that of CAK.
Molecular Weight81.6 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of PAKtide.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-650) and in bulk (cat#14-650-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-650M 04053252924552

Documentation

Produits & Applications associés

Alternative Packsize

Référence Description
14-650 PKG1β Protein, active, 10 µg

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Catégories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases