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14-508 PKCµ Recombinant Human Protein, Active, 10 µg

Active, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
14-508
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-508M when ordering the 250 µg size.
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue Number14-508
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPKCµ Recombinant Human Protein, Active, 10 µg
OverviewN-terminal His6-tagged recombinant, full length, human PKCμ.
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceHuman PKCμ expressed in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryMembers of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]
Gene Symbol
  • PRKD1
  • PKD
  • PKCM
  • nPKC-mu
  • PRKCM
  • PKC-mu
  • nPKC-D1
  • PKC-MU
  • PKD1
Protein TargetPKCµ
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q15139 # This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
SIZE: 912 amino acids; 101888 Da
SUBUNIT: Interacts via its N-terminal region with CENTA1.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: Q15139 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 PH domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.
Molecular Weight105kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of MAPKAP Kinase 2 Substrate Peptide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-508M when ordering the 250 µg size.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-508 04053252366260

Produits & Applications associés

Alternative Packsize

Référence Description
14-508M PKCµ Protein, active, 250 µg

Familles de produits

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Catégories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases