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476475 PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated

Primary Target: PKC
476475
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₆₀H₁₁₇N₂₁O₁₁

Products

RéférenceConditionnement Qté
476475-500UG Ampoule plast. 500 μg
Description
OverviewEpidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC50 = 5 µM).
Catalogue Number476475
Brand Family Calbiochem®
SynonymsMyr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
References
ReferencesWard, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
Product Information
ATP CompetitiveN
FormLyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₆₀H₁₁₇N₂₁O₁₁
Chemical formulaC₆₀H₁₁₇N₂₁O₁₁
Hygroscopic Hygroscopic
ReversibleY
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKC
Primary Target IC<sub>50</sub>5 µM against protein kinase C
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Peptide ContentY
Peptide SequenceMyr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
476475-500UG 04055977183818

Documentation

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem Certificats d'analyse

TitreNuméro de lot
476475

Références bibliographiques

Aperçu de la référence bibliographique
Ward, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-January-2010 RFH
SynonymsMyr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
DescriptionEpidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC50 = 5 µM) in intact cells.
FormLyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₆₀H₁₁₇N₂₁O₁₁
Peptide SequenceMyr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Purity≥97% by HPLC
SolubilityH₂O (5 mg/ml)
Storage Protect from moisture
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Standard Handling
ReferencesWard, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.