497985 Sigma-AldrichOrnithine Decarboxylase Inhibitor, POB - Calbiochem
The Ornithine Decarboxylase Inhibitor, POB controls the biological activity of Ornithine Decarboxylase.
More>> The Ornithine Decarboxylase Inhibitor, POB controls the biological activity of Ornithine Decarboxylase. Less<<Synonymes: N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB
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Aperçu
Replacement Information |
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Tableau de caractéristiques principal
Empirical Formula |
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C₁₉H₃₁N₃O₆ |
Products
Référence | Conditionnement | Qté | |
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497985-10MG | Flacon en verre | 10 mg |
Description | |
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Overview | A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells. |
Catalogue Number | 497985 |
Brand Family | Calbiochem® |
Synonyms | N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB |
References | |
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References | Wu, F., et al. 2007. Mol. Cancer Ther. 6, 1831. |
Product Information | |
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Form | White to off-white solid |
Formulation | Supplied as a hydrochloride salt. |
Hill Formula | C₁₉H₃₁N₃O₆ |
Chemical formula | C₁₉H₃₁N₃O₆ |
Hygroscopic | Hygroscopic |
Structure formula Image | |
Quality Level | MQ100 |
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Biological Information | |
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Purity | ≥95% by HPLC |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Référence | GTIN |
497985-10MG | 04055977199888 |
Documentation
Ornithine Decarboxylase Inhibitor, POB - Calbiochem Certificats d'analyse
Titre | Numéro de lot |
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497985 |
Références bibliographiques
Aperçu de la référence bibliographique |
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Wu, F., et al. 2007. Mol. Cancer Ther. 6, 1831. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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