Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

311203 NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem

311203
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
220805-22-1C₈H₁₈N₄O₂ . 2HCl

Products

RéférenceConditionnement Qté
311203-25MG Ampoule plast. 25 mg
Description
OverviewA cell-permeable, reversible inhibitor of nitric oxide synthase in vitro (IC50 = 2-3 µM) and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
Catalogue Number311203
Brand Family Calbiochem®
SynonymsADMA, 2HCl
References
ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.
Product Information
CAS number220805-22-1
ATP CompetitiveN
FormWhite amorphous solid
Hill FormulaC₈H₁₈N₄O₂ . 2HCl
Chemical formulaC₈H₁₈N₄O₂ . 2HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNOS in vitro
Primary Target IC<sub>50</sub>2-3 µM inhibiting nitric oxide synthase in vitro
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
311203-25MG 04055977216851

Documentation

NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem Certificats d'analyse

TitreNuméro de lot
311203

Références bibliographiques

Aperçu de la référence bibliographique
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.

Brochure

Titre
Pathways and Biomarkers of Oxidative Stress
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-June-2008 RFH
SynonymsADMA, 2HCl
DescriptionEndogenous reversible inhibitor of nitric oxide synthesis in vitro and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
FormWhite amorphous solid
Intert gas (Yes/No) Packaged under inert gas
CAS number220805-22-1
Chemical formulaC₈H₁₈N₄O₂ . 2HCl
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (50 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity Standard Handling
ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.