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399250 NG-Hydroxy-L-arginine, Monoacetate Salt - CAS 53598-01-9 - Calbiochem

Cell permeable. A key intermediate in the biosynthesis of nitric oxide by cNOS. NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450 system.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: NOHA, AcOH

Primary Target: liver and macrophage arginase
399250
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Tableau de caractéristiques principal

CAS #Empirical Formula
53598-01-9C₆H₁₄N₄O₃ · CH₃CO₂H

Products

RéférenceConditionnement Qté
399250-5MG Ampoule plast. 5 mg
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Description
OverviewCell permeable. A key intermediate in the biosynthesis of nitric oxide by constitutive nitric oxide synthase (cNOS). NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450 system. A potent inhibitor of liver and macrophage arginase (Ki = 150 µM).
Catalogue Number399250
Brand Family Calbiochem®
SynonymsNOHA, AcOH
References
ReferencesBoucher, J.L., et al. 1994. Biochem. Biophys. Res. Commun. 203, 1614.
Pufahl, R.A., and Marletta, M.A. 1993. Biochem. Biophys. Res. Commun. 193, 963.
Boucher, J.L., et al. 1992. Biochem. Biophys. Res. Commun. 187, 880.
Stuehr, D.J., et al. 1991. J. Biol. Chem. 266, 6259.
Wallace, G.C., et al. 1991. Biochem. Biophys. Res. Commun. 176, 528.
Zembowicz, A., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 11172.
Product Information
CAS number53598-01-9
FormWhite solid
Hill FormulaC₆H₁₄N₄O₃ · CH₃CO₂H
Chemical formulaC₆H₁₄N₄O₃ · CH₃CO₂H
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetliver and macrophage arginase
Primary Target K<sub>i</sub>150 µM
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Référence GTIN
399250-5MG 04055977212556