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444218 MMP-3 Inhibitor I - Calbiochem

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-3 Inhibitor I - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor

Primary Target: MMP-3
444218
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₂₇H₄₆N₁₀O₉S

Products

RéférenceConditionnement Qté
444218-5MG Ampoule plast. 5 mg
Description
OverviewInhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Catalogue Number444218
Brand Family Calbiochem®
SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
References
ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Product Information
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluroacetate salt.
Hill FormulaC₂₇H₄₆N₁₀O₉S
Chemical formulaC₂₇H₄₆N₁₀O₉S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-3
Primary Target IC<sub>50</sub>5 µM against MMP-3
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
444218-5MG 04055977205220

Documentation

MMP-3 Inhibitor I - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

MMP-3 Inhibitor I - Calbiochem Certificats d'analyse

TitreNuméro de lot
444218

Références bibliographiques

Aperçu de la référence bibliographique
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

Citations

Titre
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•
    Fiche technique

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision31-January-2008 JSW
    SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
    DescriptionInhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
    FormWhite solid
    FormulationSupplied as a trifluroacetate salt.
    Chemical formulaC₂₇H₄₆N₁₀O₉S
    Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
    Purity≥90% by HPLC
    SolubilityH₂O (1 mg/ml)
    Storage -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
    Toxicity Standard Handling
    ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
    Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•