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444287 MMP-13, Human, Recombinant, Active

MMP-13, Human, Recombinant, Active : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
444287
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Aperçu

Replacement Information

Products

RéférenceConditionnement Qté
444287-5UG Ampoule plast. 5 μg
Description
OverviewRecombinant, human MMP-13. MMP-13 is a collagenase-3 enzyme that degrades a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X, and XIV, gelatin, aggrecan, perlecan and fibronectin. It is distinguished from other human collagenases by the fact that it effectively degrades type II collagen. The importance of MMP-13 is further strengthened by reports that it is a biomarker for poor prognosis in many carcinomas and other type of cancers.
Catalogue Number444287
Brand Family Calbiochem®
References
ReferencesFreije, M.P.S., et al. 1994. J. Biol. Chem. 269,16766.
Product Information
Unit of DefinitionOne unit is defined as the amount of APMA-activated enzyme that will hydrolyze 1µmol MCA-Pro-Leu-Lys-Gly-Leu-DPA-Ala-Arg-NH₂ (Cat. No. 03-32-5032) at 37°C, pH 7.5.
FormLiquid
FormulationIn 50 mM HEPES, 10 mM CaCl₂, 20% glycerol, 0.005% BRIJ® 35 Detergent, pH 7.5. APMA-free.
Quality LevelMQ100
Applications
Biological Information
Specific Activity≥50 mU/mg protein
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
444287-5UG 04055977186048

Documentation

MMP-13, Human, Recombinant, Active FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

MMP-13, Human, Recombinant, Active Certificats d'analyse

TitreNuméro de lot
444287

Références bibliographiques

Aperçu de la référence bibliographique
Freije, M.P.S., et al. 1994. J. Biol. Chem. 269,16766.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-March-2009 JSW
DescriptionRecombinant, human MMP-13. MMP-13 is a collagenase-3 enzyme that degrades a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X, and XIV, gelatin, aggrecan, perlecan and fibronectin. It is distinguished from other human collagenases by the fact that it effectively degrades type II collagen. The importance of MMP-13 is further strengthened by reports that it is a biomarker for poor prognosis in many carcinomas and other type of cancers.
FormLiquid
FormulationIn 50 mM HEPES, 10 mM CaCl₂, 20% glycerol, 0.005% BRIJ® 35 Detergent, pH 7.5. APMA-free.
Concentration Label Please refer to vial label for lot-specific concentration
Specific activity≥50 mU/mg protein
Unit definitionOne unit is defined as the amount of APMA-activated enzyme that will hydrolyze 1µmol MCA-Pro-Leu-Lys-Gly-Leu-DPA-Ala-Arg-NH₂ (Cat. No. 03-32-5032) at 37°C, pH 7.5.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesFreije, M.P.S., et al. 1994. J. Biol. Chem. 269,16766.