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AG201 MCT4, control peptide for AB3550P

AG201
100 µg  
Purchase on Sigma-Aldrich

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Aperçu

Replacement Information

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Description
Catalogue NumberAG201
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionMCT4, control peptide for AB3550P
OverviewA 19 amino acid peptide sequence within the cytoplasmic domain of human MCT4 (1).
References
Product Information
PresentationLiquid in PBS containing 0.1% BSA and 0.1% sodium azide.
Quality LevelMQ100
Applications
Key Applications
  • Cell Function Assay
Application NotesFor use in blocking the reactivity of AB3550P.

Optimal working dilution must be determined by the end user.
Biological Information
Concentration1 mg/mL
Entrez Gene Number
Entrez Gene SummaryLactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM]
Gene Symbol
  • SLC16A3
  • MCT3
  • MGC138472
  • MGC138474
  • MCT4
UniProt Number
UniProt SummaryFUNCTION: SwissProt: O15427 # Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
SIZE: 465 amino acids; 49469 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Highly expressed in skeletal muscle.
SIMILARITY: SwissProt: O15427 ## Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
AG201 04053252512803

Documentation

MCT4, control peptide for AB3550P FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

MCT4, control peptide for AB3550P Certificats d'analyse

TitreNuméro de lot
MONOCARBOXYLATE TRANSPORTER 5 - 4175178 4175178
MONOCARBOXYLATE TRANSPORTER 5 -2761529 2761529
MONOCARBOXYLATE TRANSPORTER 5 CONTROL PEPTIDE - 2109544 2109544

Références bibliographiques

Aperçu de la référence bibliographiqueNº PubMed
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation.
Halestrap, A P and Price, N T
Biochem. J., 343 Pt 2: 281-99 (1999)  1998

Afficher le résumé
10510291 10510291