428021 Sigma-AldrichLatrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
More>> Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM). Less<<FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Produits recommandés
Aperçu
| Replacement Information |
|---|
Tableau de caractéristiques principal
| CAS # | Empirical Formula |
|---|---|
| 76343-93-6 | C₂₂H₃₁NO₅S |
Products
| Référence | Conditionnement | Qté | |
|---|---|---|---|
| 428021-100UG | Ampoule plast. | 100 μg |
| Description | |
|---|---|
| Overview | A cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos. A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428026 in DMSO is also available. |
| Catalogue Number | 428021 |
| Brand Family | Calbiochem® |
| Product Information | |
|---|---|
| CAS number | 76343-93-6 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₂₂H₃₁NO₅S |
| Chemical formula | C₂₂H₃₁NO₅S |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Primary Target | G-actin |
| Primary Target IC<sub>50</sub> | Kd = 200 nM in formation of a 1:1 complex with monomeric G-actin |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information | |
|---|---|
| R Phrase | R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
| S Phrase | S: 36 Wear suitable protective clothing. |
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Référence | GTIN |
| 428021-100UG | 07790788050214 |
Documentation
Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem FDS
| Titre |
|---|
Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem Certificats d'analyse
| Titre | Numéro de lot |
|---|---|
| 428021 |
Références bibliographiques
| Aperçu de la référence bibliographique |
|---|
| Ayscough, K.R., et al. 1997. J. Cell Biol. 137, 399. Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127. Coue, M., et al. 1987. FEBS Lett. 213, 316. Schatten, G., et al. 1986. Exp. Cell Res. 166, 191. Spector, I., et al. 1983. Science 219, 493. |