Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

407621 IL-2Rα Antagonist - CAS 1217448-66-2 - Calbiochem

407621
Purchase on Sigma-Aldrich

Aperçu

Tableau de caractéristiques principal

CAS #Empirical Formula
1217448-66-2C₂₆H₃₀N₄O₃ • CF₃CO₂H

Products

RéférenceConditionnement Qté
407621-5MG Ampoule plast. 5 mg
Description
OverviewA non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC50 = 3 µM).
Catalogue Number407621
Brand Family Calbiochem®
Synonyms(R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550
References
ReferencesEmerson, S.D., et al. 2003. Protein Science 12, 811.
Tilley, J.W., et al. 1997. J. Am. Chem. Soc. 119, 7589.
Product Information
CAS number1217448-66-2
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₆H₃₀N₄O₃ • CF₃CO₂H
Chemical formulaC₂₆H₃₀N₄O₃ • CF₃CO₂H
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetInhibitor of the IL-2/IL-2Rα interaction
Primary Target IC<sub>50</sub>3 µM against IL-2/IL-2Rα interaction
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Référence GTIN
407621-5MG 04055977211368