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401478 IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem

An inactive control for IκB Kinase Inhibitor Peptide.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Ac-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂

Primary Target: An inactive control for IκB Kinase Inhibitor Peptide
401478
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₁₃₈H₂₂₉N₃₇O₄₃S

Products

RéférenceConditionnement Qté
401478-1MG Ampoule plast. 1 mg
Description
OverviewAn inactive control for IκB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IκB (Ser32→Ala and Ser36→Ala) fused to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml.
Catalogue Number401478
Brand Family Calbiochem®
SynonymsAc-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
References
ReferencesSwaroop, N., et al. 2001. Pharm. Res. 18, 1631.
Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.
Product Information
ATP CompetitiveN
FormOff-white to white solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₃₈H₂₂₉N₃₇O₄₃S
Chemical formulaC₁₃₈H₂₂₉N₃₇O₄₃S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetAn inactive control for IκB Kinase Inhibitor Peptide
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
401478-1MG 04055977211931

Documentation

IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem Certificats d'analyse

TitreNuméro de lot
401478

Références bibliographiques

Aperçu de la référence bibliographique
Swaroop, N., et al. 2001. Pharm. Res. 18, 1631.
Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-July-2014 JSW
SynonymsAc-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
DescriptionAn inactive control for IkB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IkB (Ser32 → Ala and Ser36 → Ala), linked to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml.
FormOff-white to white solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₃₈H₂₂₉N₃₇O₄₃S
Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂
Purity≥97% by HPLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSwaroop, N., et al. 2001. Pharm. Res. 18, 1631.
Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.