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368056 Granzyme B Inhibitor IV - Calbiochem

The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

Granzyme B Inhibitor IV - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Ac-IEPD-CHO, Caspase-8 inhibitor III

Primary Target: granzyme B
368056
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₂₂H₃₄N₄O₉

Products

RéférenceConditionnement Qté
368056-1MG Ampoule plast. 1 mg
Description
OverviewA reversible inhibitor of granzyme B and caspase-8.
Catalogue Number368056
Brand Family Calbiochem®
SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
References
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₂H₃₄N₄O₉
Chemical formulaC₂₂H₃₄N₄O₉
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetgranzyme B
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
368056-1MG 04055977192148

Documentation

Granzyme B Inhibitor IV - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Granzyme B Inhibitor IV - Calbiochem Certificats d'analyse

TitreNuméro de lot
368056

Références bibliographiques

Aperçu de la référence bibliographique
Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Brochure

Titre
Caspases and other Apoptosis Related Tools Brochure
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-July-2008 RFH
SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
DescriptionA reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.
FormWhite solid
Chemical formulaC₂₂H₃₄N₄O₉
Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.