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345736 Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem

345736
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₈₄H₁₄₆N₄O₃₉ · 2NH₄

Products

RéférenceConditionnement Qté
345736-1MG Ampoule plast. 1 mg
Description
OverviewUseful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.
Catalogue Number345736
Brand Family Calbiochem®
SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
References
ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.
Product Information
ATP CompetitiveN
FormLyophilized
Hill FormulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetProtein kinase C
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
345736-1MG 04055977193831

Documentation

Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem Certificats d'analyse

TitreNuméro de lot
345736

Références bibliographiques

Aperçu de la référence bibliographique
Longee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.

Brochure

Titre
Gangliosides Technical Bulletin
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-September-2007 JSW
SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
DescriptionDisialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.

Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.
FormLyophilized
Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityChloroform:Methanol (2:1) or DMSO. For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity Irritant
ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.