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14-715M GRK6 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, full length human GRK6, for use in Kinase Assays.

GRK6 Protein, active, 250 µg : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
14-715M
250 µg  Also available in 10 μg size (cat#14-715) and in bulk (cat# 14-715-K).
Purchase on Sigma-Aldrich

Aperçu

Replacement Information
Description
Catalogue Number14-715M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionGRK6 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, full length human GRK6

G protein coupled receptor kinase
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, full length human GRK6, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.
Gene Symbol
  • GRK6
  • FLJ32135
  • GPRK6
Protein TargetGRK6
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P43250 # Specifically phosphorylates the activated forms of G protein-coupled receptors.
SIZE: 576 amino acids; 65991 Da
SUBCELLULAR LOCATION: Membrane; Lipid-anchor.
TISSUE SPECIFICITY: Widely expressed.
PTM: It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
SIMILARITY: SwissProt: P43250 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
Molecular Weight69.8kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of casein
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-715) and in bulk (cat# 14-715-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
14-715M 04053252681615

Produits & Applications associés

Alternative Packsize

Référence Description
14-715 GRK6 Protein, active, 10 µg

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Catégories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases