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324904 Epiregulin, Mouse, Recombinant

Epiregulin, Mouse, Recombinant is expressed in E. coli with an N-terminal methionine. Inhibits epithelial tumor growth and stimulates the growth of fibroblasts and other cell types.

Epiregulin, Mouse, Recombinant : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
324904
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

Purity
≥97% by SDS-PAGE

Products

RéférenceConditionnement Qté
324904-50UG Flacon en verre 50 μg
Description
OverviewRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
Catalogue Number324904
Brand Family Calbiochem®
References
ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
Product Information
FormLiquid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
324904-50UG 04055977196276

Documentation

Epiregulin, Mouse, Recombinant FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Epiregulin, Mouse, Recombinant Certificats d'analyse

TitreNuméro de lot
324904

Références bibliographiques

Aperçu de la référence bibliographique
Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-Sepmtember-2011 RFH
DescriptionRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
FormLiquid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg protein
Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
SolubilityReconstitute to 10 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.