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309795 DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na

Primary Target: Cl- uptake
309795
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
53005-05-3C₁₆H₈N₂O₆S₄ · 2Na

Products

RéférenceConditionnement Qté
309795-250MG Ampoule plast. 250 mg
Description
OverviewBinds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Catalogue Number309795
Brand Family Calbiochem®
Synonyms4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na
References
ReferencesBettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
Product Information
CAS number53005-05-3
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₆H₈N₂O₆S₄ · 2Na
Chemical formulaC₁₆H₈N₂O₆S₄ · 2Na
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCl- uptake
Primary Target IC<sub>50</sub>150 nM inhibiting Cl- uptake in neuroblastoma cells
Purity≥85% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
309795-250MG 04055977216790

Documentation

DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem Certificats d'analyse

TitreNuméro de lot
309795

Références bibliographiques

Aperçu de la référence bibliographique
Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-February-2024 JSW
Synonyms4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na
DescriptionBinds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl- uptake (IC50 = 150 nM) in neuroblastoma cells. Has antiulcerous activity.
FormYellow solid
CAS number53005-05-3
Chemical formulaC₁₆H₈N₂O₆S₄ · 2Na
Structure formulaStructure formula
Purity≥85% by HPLC
SolubilityH₂O (0.5%)
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
ReferencesBettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.