Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

567727 D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
567727
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
26993-30-6C₁₈H₃₈NO₅P

Products

RéférenceConditionnement Qté
567727-1MG Ampoule plast. 1 mg
Description
OverviewA putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway. Activates phospholipase D (PLD) and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss/3T3 fibroblasts. Inhibits activation of caspases that cleave PARP and lamins during Fas- and ceramide-mediated apoptosis.
Catalogue Number567727
Brand Family Calbiochem®
References
ReferencesCuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.
Product Information
CAS number26993-30-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₈H₃₈NO₅P
Chemical formulaC₁₈H₃₈NO₅P
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMobilizes calcium from intracellular stores
Purity≥95% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and evaporate under a stream of nitrogen. Store at -20°C. Prior to use, dissolve in 4 mg/ml BSA solution with vortexing. Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
567727-1MG 07790788051679

Documentation

D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem Certificats d'analyse

TitreNuméro de lot
567727

Références bibliographiques

Aperçu de la référence bibliographique
Cuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.

Brochure

Titre
Bioactive Lipids Technical Bulletin
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-September-2008 RFH
DescriptionA putative second messenger that mobilizes calcium from intracellular stores via an IP3 independent pathway. Activates phospholipase D and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss 3T3 fibroblasts.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number26993-30-6
Chemical formulaC₁₈H₃₈NO₅P
Structure formulaStructure formula
Purity≥95% by TLC
SolubilityMethanol (0.5 mg/ml). Slight warming and vortexing may be required.
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and evaporate under a stream of nitrogen. Store at -20°C. Prior to use, dissolve in 4 mg/ml BSA solution with vortexing. Stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
ReferencesCuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.