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219365 Coagulation Factor V, Human Plasma

Coagulation Factor V, Human Plasma, CAS 9001-24-5, is a native coagulation factor V that is cleaved by thrombin to yield activated Factor Va that is 50-fold greater activity than its precursor form.

Coagulation Factor V, Human Plasma : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Proaccelerin, Labile Factor, Ac-globulin, Ac-g

219365
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Aperçu

Replacement Information

Products

RéférenceConditionnement Qté
219365-100UG Ampoule plast. 100 μg
Description
OverviewNative coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors that form a "prothrombinase" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin.
Catalogue Number219365
Brand Family Calbiochem®
SynonymsProaccelerin, Labile Factor, Ac-globulin, Ac-g
References
ReferencesWalker, F.J. 1992. J. Biol. Chem. 267, 19896.
Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem. 265, 17132.
Krishnaswamy, S., et al. 1989. J. Biol. Chem. 264, 3160.
Lee, C.D., and Mann, K.G. 1989. Blood 73, 185.
Krieg, U.C., et al. 1987. Biochemistry 26, 103.
Product Information
CAS number9001-24-5
FormLiquid
FormulationIn 50% glycerol/H₂O (v/v).
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥20 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store below -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
219365-100UG 04055977202229

Documentation

Coagulation Factor V, Human Plasma FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Coagulation Factor V, Human Plasma Certificats d'analyse

TitreNuméro de lot
219365

Références bibliographiques

Aperçu de la référence bibliographique
Walker, F.J. 1992. J. Biol. Chem. 267, 19896.
Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem. 265, 17132.
Krishnaswamy, S., et al. 1989. J. Biol. Chem. 264, 3160.
Lee, C.D., and Mann, K.G. 1989. Blood 73, 185.
Krieg, U.C., et al. 1987. Biochemistry 26, 103.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2008 RFH
SynonymsProaccelerin, Labile Factor, Ac-globulin, Ac-g
DescriptionNative coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors which form a "prothrombinase" complex with Factor Xa, enabling its proteolytic activation of prothrombin to thrombin.
FormLiquid
FormulationIn 50% glycerol/H₂O (v/v).
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9001-24-5
Purity≥95% by SDS-PAGE
Specific activity≥20 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store below -20°C.
Toxicity Standard Handling
Merck USA index14, 3919
ReferencesWalker, F.J. 1992. J. Biol. Chem. 267, 19896.
Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem. 265, 17132.
Krishnaswamy, S., et al. 1989. J. Biol. Chem. 264, 3160.
Lee, C.D., and Mann, K.G. 1989. Blood 73, 185.
Krieg, U.C., et al. 1987. Biochemistry 26, 103.