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218735 Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem

The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Ac-VAD-CHO

Primary Target: pan-caspase
218735
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
147837-52-3C₁₄H₂₃N₃O₆

Products

RéférenceConditionnement Qté
218735-1MG Ampoule plast. 1 mg
Description
OverviewA potent and reversible pan-caspase inhibitor.
Catalogue Number218735
Brand Family Calbiochem®
SynonymsAc-VAD-CHO
References
ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Product Information
CAS number147837-52-3
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₄H₂₃N₃O₆
Chemical formulaC₁₄H₂₃N₃O₆
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetpan-caspase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Val-Ala-Asp-CHO
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
218735-1MG 04055977218978

Documentation

Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem Certificats d'analyse

TitreNuméro de lot
218735

Références bibliographiques

Aperçu de la référence bibliographique
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Brochure

Titre
Caspases and other Apoptosis Related Tools Brochure

Citations

Titre
  • So-Young Park and Adriana Ferreira. (2005) The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which Tau mediates β-amyloid-induced neurodegeneration. Journal of Neuroscience 25, 5365-5375.
    		•
    Fiche technique

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision11-March-2011 RFH
    SynonymsAc-VAD-CHO
    DescriptionA potent and reversible inhibitor of caspases.
    FormWhite solid
    CAS number147837-52-3
    Chemical formulaC₁₄H₂₃N₃O₆
    Peptide SequenceAc-Val-Ala-Asp-CHO
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO (150 mg/ml)
    Storage -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    Toxicity Standard Handling
    ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
    Citation
  • So-Young Park and Adriana Ferreira. (2005) The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which Tau mediates β-amyloid-induced neurodegeneration. Journal of Neuroscience 25, 5365-5375.
    		•