Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

218753 Caspase-5 Inhibitor I

Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.

Caspase-5 Inhibitor I : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Z-WE(OMe)HD(OMe)-FMK

Primary Target: caspase-1, caspase-4, caspase-5, caspase-8
218753
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₃₇H₄₂FN₇O₁₀

Products

RéférenceConditionnement Qté
218753-1MG Ampoule plast. 1 mg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
Catalogue Number218753
Brand Family Calbiochem®
SynonymsZ-WE(OMe)HD(OMe)-FMK
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Product Information
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₃₇H₄₂FN₇O₁₀
Chemical formulaC₃₇H₄₂FN₇O₁₀
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-1, caspase-4, caspase-5, caspase-8
Puritysingle spot by TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
218753-1MG 04055977219098

Documentation

Caspase-5 Inhibitor I FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Caspase-5 Inhibitor I Certificats d'analyse

TitreNuméro de lot
218753

Références bibliographiques

Aperçu de la référence bibliographique
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.

Brochure

Titre
Caspases and other Apoptosis Related Tools Brochure
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-June-2008 JSW
SynonymsZ-WE(OMe)HD(OMe)-FMK
DescriptionA potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₃₇H₄₂FN₇O₁₀
Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Puritysingle spot by TLC
SolubilityDMSO (5 mg/ml)
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Toxicity Standard Handling
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.