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211280 Capsazepine - CAS 138977-28-3 - Calbiochem

211280
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
138977-28-3C₁₉H₂₁N₂O₂SCl

Products

RéférenceConditionnement Qté
211280-10MG Ampoule plast. 10 mg
Description
OverviewA competitive antagonist of Capsaicin (Cat. No. 211274) and resiniferatoxin. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
Catalogue Number211280
Brand Family Calbiochem®
SynonymsN-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
References
ReferencesFox, A.J., et al. 1995. Neuroscience 67, 741.
Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.
Product Information
CAS number138977-28-3
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₉H₂₁N₂O₂SCl
Chemical formulaC₁₉H₂₁N₂O₂SCl
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA competitive antagonist of Capsaicin and resiniferatoxin
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
211280-10MG 04055977219180

Documentation

Capsazepine - CAS 138977-28-3 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Capsazepine - CAS 138977-28-3 - Calbiochem Certificats d'analyse

TitreNuméro de lot
211280

Références bibliographiques

Aperçu de la référence bibliographique
Fox, A.J., et al. 1995. Neuroscience 67, 741.
Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-November 2016 JSW
SynonymsN-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
DescriptionA competitive antagonist of the sensory neuron excitants capsaicin (Cat. No. 211274) and resiniferatoxin (Cat. No. 553975). Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
FormOff-white solid
CAS number138977-28-3
Chemical formulaC₁₉H₂₁N₂O₂SCl
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO or Methanol
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Standard Handling
ReferencesFox, A.J., et al. 1995. Neuroscience 67, 741.
Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
Walpole, C.S.J., et al. 1994. J. Med. Chem. 37, 1942.
Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap. 267, 728.