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211275 Capsaicin

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons.

Capsaicin : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

211275
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
404-86-4C₁₈H₂₇NO₃

Products

RéférenceConditionnement Qté
211275-100MG Flacon en verre 100 mg
Description
OverviewAn active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
Catalogue Number211275
Brand Family Calbiochem®
Synonyms[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
References
ReferencesSingh, S., et al. 1996. J. Immunol. 157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
Pernow, B., et al. 1985. J. Immunol. 135, 8125.
Product Information
CAS number404-86-4
FormWhite to pale yellow solid
Hill FormulaC₁₈H₂₇NO₃
Chemical formulaC₁₈H₂₇NO₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSRA8530000
Safety Information
R PhraseR: 25-41-48

Toxic if swallowed.
Risk of serious damage to eyes.
Danger of serious damage to health by prolonged exposure.
S PhraseS: 26-36/37/39-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
211275-100MG 04055977219173

Documentation

Capsaicin FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Capsaicin Certificats d'analyse

TitreNuméro de lot
211275

Références bibliographiques

Aperçu de la référence bibliographique
Singh, S., et al. 1996. J. Immunol. 157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
Pernow, B., et al. 1985. J. Immunol. 135, 8125.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-February-2020 JSW
Synonyms[(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
DescriptionAn active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.
FormWhite to pale yellow solid
CAS number404-86-4
RTECSRA8530000
Chemical formulaC₁₈H₂₇NO₃
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityEthanol
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Toxic
Merck USA index14, 1768
ReferencesSingh, S., et al. 1996. J. Immunol. 157, 4412.
Nakazawa, K., et al. 1994. Br. J. Pharmacol. 113, 296.
Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci. 12, 517.
Takaki, M., et al. 1994. J. Mol. Cell. Cardiol. 26, 1227.
Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci. 11, 330.
Pernow, B., et al. 1985. J. Immunol. 135, 8125.