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208900 Calpastatin, Human, Recombinant, Domain I - Calbiochem

Domain I of human calpastatin.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Primary Target: calpain-1
208900
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Products

RéférenceConditionnement Qté
208900-1MG Flacon en verre 1 mg
Description
OverviewDomain I of human calpastatin. Endogenous protease inhibitor that acts specifically on Calpain-1 (Cat. No. 208712). Exhibits greater inhibitory potency than calpain inhibitors I and II.
Catalogue Number208900
Brand Family Calbiochem®
References
ReferencesSalamino, F., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1326.
Uemori, T., et al. 1990. Biochem. Biophys. Res. Commun. 166, 1485.
Asada, K., et al. 1989. J. Enzyme Inhib. 3, 49.
Product Information
ATP CompetitiveN
DeclarationNot available for sale in Japan.
FormWhite lyophilized solid
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Biological activity50 nM completely inhibits the activity of 7.5 µg/ml calpain I
Primary Targetcalpain-1
Purityhomogeneous by SDS-PAGE
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
208900-1MG 04055977219494

Documentation

Calpastatin, Human, Recombinant, Domain I - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Calpastatin, Human, Recombinant, Domain I - Calbiochem Certificats d'analyse

TitreNuméro de lot
208900

Références bibliographiques

Aperçu de la référence bibliographique
Salamino, F., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1326.
Uemori, T., et al. 1990. Biochem. Biophys. Res. Commun. 166, 1485.
Asada, K., et al. 1989. J. Enzyme Inhib. 3, 49.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-May-2008 RFH
DescriptionAn endogenous protease inhibitor that acts specifically on Calpain I (Cat. No. 208712), a Ca2+-dependent cysteine protease. Widely distributed in mammalian and avian cells. Has better inhibitory action than Calpain Inhibitor I (Cat. No. 208719) and Calpain Inhibitor II (Cat. No. 208721). Calpastatin corresponds to domain I of human calpastatin. The inhibitory sequence of human domain I consists of at least 18 amino acid residues.
FormWhite lyophilized solid
Purityhomogeneous by SDS-PAGE
Biological activity50 nM completely inhibits the activity of 7.5 µg/ml calpain I
SolubilityH₂O (1 mg/ml) or Aqueous Buffers (1 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSalamino, F., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1326.
Uemori, T., et al. 1990. Biochem. Biophys. Res. Commun. 166, 1485.
Asada, K., et al. 1989. J. Enzyme Inhib. 3, 49.