208293 Sigma-AldrichCalcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem
The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel.
More>> The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel. Less<<FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Synonymes: TMEM16 Blocker I, ANO Blocker I, Anoctamin Blocker I, 6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid, CaCC Blocker I
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Aperçu
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Tableau de caractéristiques principal
| CAS # | Empirical Formula |
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| 407587-33-1 | C₁₈H₂₁NO₄S |
Products
| Référence | Conditionnement | Qté | |
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| 208293-10MG | Flacon en verre | 10 mg |
| Description | |
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| Overview | An aminothiophene that inhibits Calcium-activated Chloride Channel (CaCC) current influx induced by multiple calcium-elevating agonists (IC50 = 10 µM) without inhibiting calcium elevation, and CaMKII and CFTR activity. Inhibits CaCC chloride response following agonist stimulation in human bronchial and intestinal epithelial cells. Also demonstrates an inhibitory effect on TMEM16A channels (IC50 = 2.1 µM). Also available as a 100 mM solution in DMSO (Cat. No. 508628). |
| Catalogue Number | 208293 |
| Brand Family | Calbiochem® |
| Synonyms | TMEM16 Blocker I, ANO Blocker I, Anoctamin Blocker I, 6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid, CaCC Blocker I |
| References | |
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| References | Fuente, R., et al. 2011, Mol Pharmacol. 73, 758. Namkung, W., et al. 2011, J Biol Chem. 286, 2365. |
| Product Information | |
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| CAS number | 407587-33-1 |
| Form | Off-white solid |
| Hill Formula | C₁₈H₂₁NO₄S |
| Chemical formula | C₁₈H₂₁NO₄S |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥98% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Référence | GTIN |
| 208293-10MG | 04055977203264 |
Documentation
Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem FDS
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Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem Certificats d'analyse
| Titre | Numéro de lot |
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| 208293 |
Références bibliographiques
| Aperçu de la référence bibliographique |
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| Fuente, R., et al. 2011, Mol Pharmacol. 73, 758. Namkung, W., et al. 2011, J Biol Chem. 286, 2365. |