Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

205546 Caffeic Acid - CAS 331-39-5 - Calbiochem

A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.

Caffeic Acid - CAS 331-39-5 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 3,4-Dihydroxycinnamic Acid

Primary Target: 5-lipoxygenase
205546
Purchase on Sigma-Aldrich

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
331-39-5C₉H₈O₄

Products

RéférenceConditionnement Qté
205546-500MG Ampoule plast. 500 mg
Description
OverviewA natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
Catalogue Number205546
Brand Family Calbiochem®
Synonyms3,4-Dihydroxycinnamic Acid
References
ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
Product Information
CAS number331-39-5
ATP CompetitiveN
FormTan crystalline solid
Hill FormulaC₉H₈O₄
Chemical formulaC₉H₈O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-lipoxygenase
Primary Target IC<sub>50</sub>3.7 µM against 5-lipoxygenase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGD8950000
Safety Information
R PhraseR: 40

Limited evidence of a carcinogenic effect.
S PhraseS: 36/37

Wear suitable protective clothing and gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
205546-500MG 04055977203134

Documentation

Caffeic Acid - CAS 331-39-5 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

Caffeic Acid - CAS 331-39-5 - Calbiochem Certificats d'analyse

TitreNuméro de lot
205546

Références bibliographiques

Aperçu de la référence bibliographique
Yamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2008 RFH
Synonyms3,4-Dihydroxycinnamic Acid
DescriptionA cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
FormTan crystalline solid
Intert gas (Yes/No) Packaged under inert gas
CAS number331-39-5
RTECSGD8950000
Chemical formulaC₉H₈O₄
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml) or Ethanol (50 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
Merck USA index14, 1635
ReferencesYamanaka, N., et al. 1997. FEBS Lett. 405, 186.
Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.