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220201 CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem

CAS 75621-03-3 is a zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

220201
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
75621-03-3C₃₂H₅₈N₂O₇S

Products

RéférenceConditionnement Qté
220201-10GM Flacon plastique 10 gm
220201-1GM Flacon plastique 1 gm
220201-1KG Flacon plastique 1 kg
220201-250GM Flacon plastique 250 gm
220201-25GM Flacon plastique 25 gm
220201-5GM Flacon plastique 5 gm
Description
OverviewZwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than structurally-related carboxylic acid anions and is much more effective at breaking protein-protein interactions than either sodium cholate or TRITON® X-100 Detergent. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Also, capable of disaggregating cytochrome P450 to its monomeric form without denaturation. Has a small micellar molecular weight and a high critical micellar concentration and can be removed from either gels or protein solutions by dialysis across a membrane. Aggregation number: 4-14.
Conductivity (1.0 M, 24°C): <100 µmhos.
Catalogue Number220201
Brand Family Calbiochem®
Synonyms3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
References
ReferencesChen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.
Product Information
CAS number75621-03-3
Aggregation Number4 - 14
CMC6 - 10 mM
FormWhite crystalline powder
Hill FormulaC₃₂H₅₈N₂O₇S
Chemical formulaC₃₂H₅₈N₂O₇S
Hygroscopic Hygroscopic
Micellar weight6150
Quality LevelMQ300
Applications
Biological Information
Purity≥98% by NMR
Physicochemical Information
ContaminantsDNase, RNase, and Protease: none detected
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 22-36/38

Harmful if swallowed.
Irritating to eyes and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Référence GTIN
220201-10GM 07790788048754
220201-1GM 04055977200973
220201-1KG 04055977200980
220201-250GM 04055977201017
220201-25GM 04055977201000
220201-5GM 04055977201024

Documentation

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem FDS

Titre

Fiche de données de sécurité des matériaux (FDS) 

CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem Certificats d'analyse

TitreNuméro de lot
220201

Références bibliographiques

Aperçu de la référence bibliographique
Chen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.

Brochure

Titre
Biological Detergents Brochure
Bulk Product Guide
CALBIOSORBﾙ Technical Bulletin
Fiche technique

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-November-2010 RFH
Synonyms3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
DescriptionNon-denaturing zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than the structurally related carboxylic acid anions, and is more effective at breaking protein-protein interactions than either sodium cholate or TRITON® X-100. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding to opiates. Also capable of disaggregating P 450 to its monomeric form without denaturation. Has a small micellar molecular weight (6150 Daltons) and a high critical micellar concentration (6-10 mM). Can be removed from either gels or protein solutions by dialysis. Aggregation number: 4-14.
FormWhite crystalline powder
CAS number75621-03-3
Chemical formulaC₃₂H₅₈N₂O₇S
Purity≥98% by NMR
ContaminantsDNase, RNase, and Protease: none detected
SolubilityH₂O (1.0 M)
Storage +15°C to +30°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Toxicity Harmful
Merck USA index14, 2044
ReferencesChen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623.